It is prepared by the reaction of two equivalents of phenol with one equivalent of acetone. FDAs current perspective, based on its most recent safety assessment, is that BPA is safe at the current levels occurring in foods. NIEHS sponsors and co-sponsors scientific meetings, conferences, and events throughout the year. To address these questions the National Toxicology Program, partnering with FDAs National Center for Toxicological Research is carrying out in-depth studies to answer key questions and clarify uncertainties about BPA. BPA has also been found to act as an agonist of the GPER (GPR30). At 830C). Sign in to download full-size image :30583-72-3 Molecular formula:C18H33ClO3 Molecular weight: 332.91 Appearance:Colorless liquid Assay 60% Hydrogenated Bisphenol A Epoxy Resin Specification: Hydrogenated Bisphenol A Epoxy Resin Application Alternatively, and to a much lesser extent, BPA may be ethoxylated and then converted to its diacrylate and dimethacrylate derivatives (bis-EMA, or EBPADMA). [2][7] BPA is produced on an industrial scale by the condensation of phenol and acetone, and has a global production scale which is expected to reach 10 million tonnes in 2022.[8]. Copyright 2022 ChemicalBook. Based on FDAs ongoing safety review of scientific evidence, the available information continues to support the safety of BPA for the currently approved uses in food containers and packaging. In July, 2012, FDA took this action in response to a food additive petition filed by the American Chemistry Council (ACC) [9]. As a result, many exploratory scientific studies have appeared in the public literature. Epub 2014 Feb 4. b) Delclos KB, Camacho L, Lewis SM, Vanlandingham MM, Latendresse JR, Olson GR, Davis KJ, Patton RE, Gamboa da Costa G, Woodling KA, Bryant MS, Chidambaram M, Trbojevich R, Juliar BE, Felton RP, Thorn BT. Epoxy resin is based on epichlorhydrin and bisphenol A. [103], BPA is an environmental contaminant of emerging concern. FDA continues to review the available information and studies on BPA. If you are giving a presentation about an environmental health topic or An amendment of the food additive regulations based on abandonment is not based on safety, but is based on the fact that the regulatory authorization is no longer necessary for the specific use of the food additive because that use has been permanently and completely abandoned. More than 140,000 products, 270,000 supply sources and 4,400 company addresses. Epoxy Composites: Additives for High Performance, Epoxy Resins: A to Z Technical Review of Thermosetting Polymer, Synthesis of Epoxy Monomer from Bisphenol A and Epichlorohydrin, Be the first to comment on "Epoxy Resins: A to Z Technical Review of Thermosetting Polymer", carboxyl-terminated butadiene acrylonitrile copolymer (CTBNs), Powdered metals to improve electrical and thermal conductivity, Silica for cost reduction, and strength enhancement, Talc and calcium carbonate cost reduction, Carbon and graphite powders to increase lubricity, Particle characteristics (size, share, surface area), Extremely strong and good flexural strength, The hardener and the temperature determine epoxy resin cure time, Resistant to wear, cracking, peeling, corrosion and damage from chemical and environmental degradation, Has a bonding strength of up to 2,000 psi, Generally, costs slightly less than epoxy resin, Off-gases VOCs and has strong, flammable fumes, Bonding strength of polyester resin is generally less than 500 psi, Once cured, polyester resin is water permeable, meaning water can pass through it eventually, Better adhesive properties (the ability to bond to the reinforcement or core), Superior mechanical properties (particularly strength and stiffness), Improved resistance to fatigue and micro cracking, Reduced degradation from water ingress (diminution of properties due to water penetration), Increased resistance to osmosis (surface degradation due to water permeability), Natural oil-based (soybean, linseed, castor). Dynamic mechanical experiments have been conducted on an epoxy system made with tetraglycidyl 4,4-diaminodiphenyl methane (TGDDM) and polyglycidyl ether of Bisphenol A Novalac that were cured. This group may lie within the body of the molecule but is usually terminal. Bisphenol A (BPA, 80-05-7) is an organic compound used predominantly in the production of products made of polycarbonate plastic and epoxy resins that line food and beverage cans. At last,Bisphenol A epoxy resin() safety, risk, hazard and . In particular, infants are considered to be at greater risk,[83] leading to bans on the use of BPA in baby bottles and related products by the US,[84] Canada,[85] and EU[86] amongst others. [42] This process converts the individual molecules of BPA into large polymer chains, effectively trapping them. Epoxy resins made with BPA are tough and readily adhere to metal surfaces, making them excellent materials for protective coatings. FDAs Studies. 2010 Sep 1;247(2):158-65. d) Doerge DR, Twaddle NC, Vanlandingham M, Brown RP, Fisher JW. . The National Institute of Environmental Health Sciences (NIEHS) is expanding and accelerating its contributions to scientific knowledge of human health and the environment, and to the health and well-being of people everywhere. Food cans and other metal containers may be coated with epoxy resin linings made with BPA to help prevent direct food contact with metal, which helps protect food from contamination and spoilage. Bisphenol-A, commonly abbreviated as BPA, is an organic compound with the chemical formula (CH 3) 2 C (C 6 H 4 OH) 2 belonging to the group of diphenylmethane derivatives and bisphenols, with two hydroxyphenyl groups. [9][10] The manufacturing of epoxy resins and vinyl ester resins account for 2530% of BPA use. BPA is an important industrial chemical, which is mainly used as a raw material of polycarbonate and epoxy resin. BPA is also found in epoxy resins, which act as a protective lining on the inside of some metal-based food and beverage cans. The degree to which BPA leaches from polycarbonate bottles into liquid may depend more on the temperature of the liquid or bottle, than the age of the container. Distillation and vacuum distillation are used to remove toluene and unreacted epichlorohydrin, respectively. Polycarbonate drinks containers are also a source of exposure, although most disposable drinks bottles are actually made of PET, which contains no BPA. Chemical Formula . Explore thermosetting epoxy resins in detail along with their key properties and understand what makes them an ideal choice in so many applications. Product. Comparison of life-stage-dependent internal dosimetry for bisphenol a, ethinyl estradiol, a reference estrogen, and endogenous estradiol to test an estrogenic mode of action in Sprague Dawley rats. [12][13][14] BPA is a xenoestrogen, exhibiting hormone-like properties that mimic the effects of estrogen in the body. Health care providers depend on medical devices and equipment made with BPA for a transparent view within the human body so they can check for the presence of air bubbles or other obstructions during medical procedures. #12-03 Keck Seng Tower, Over the following decade, coatings and resins derived from similar materials were described by workers at the companies of DeTrey Freres in Switzerland and DeVoe and Raynolds in the US. Bisphenol A epoxy resin is the most common type for concrete coatings because of its excellent adhesion, toughness, abrasion resistance, and chemical resistance. [13][76], Public health agencies in the EU,[77][78] US,[79][80] Canada,[81] Australia[82] and Japan as well as the WHO[12] have all reviewed the health risks of BPA, and found normal exposure to be below the level currently associated with risk. While they have high mechanical strength values similar to epoxy resins, they are easy to apply similar to unsaturated polyester resins. . The condensation of acetone (hence the suffix 'A' in the name)[32] with two equivalents of phenol is catalyzed by a strong acid, such as concentrated hydrochloric acid, sulfuric acid, or a solid acid resin such as the sulfonic acid form of polystyrene sulfonate. BPA can be found in a range of products, such as: plastic food storage containers, including: pitchers. The ACC mark, Responsible Care, the hands logo mark, CHEMTREC, TRANSCAER, and americanchemistry.com are registered service marks of the American Chemistry Council, Inc. May also be known as: Polycarbonate, Epoxy Resins. When dropping is completed within half an hour, heat it for 12-24 hours under temperature 70-80C Stop the heating after bisphenol A is completely disappeared validated by TLC method. What chemicals are in epoxy resin when you consider this? The ACC petition demonstrated, from publicly available information and information collected from industry sources, that the use of polycarbonate resins in baby bottles and sippy cups had been abandoned. [15] Although the effect is very weak,[16] the pervasiveness of BPA-containing materials raises concerns, as exposure is effectively lifelong. [33] An excess of phenol is used to ensure full condensation and to limit the formation of byproducts, such as Dianin's compound. Properties of copolymer epoxy resins. It may also be used as an ingredient in some resins, which can act as a lining on the inside of some metal food and drink cans. With more than half of the global demand, the Asian market will . Epoxy resins have many uses including engineering applications such as electrical laminates for printed circuit boards, composites, paints and adhesives, as well as in a variety of protective coatings. [90] This may be the mechanism by which BPA acts as a xenoestrogen. We provide Bisphenol A epoxy resin safety data sheet view and download for free at Echemi.com. The primary source of exposure to BPA for most people is through the diet. 40:35-40. Order: 200 kg Qingdao Cemo Technology Develop Co., Ltd. . It is also a component in metal can coatings, which protect the food from directly contacting metal surfaces. bisphenol A type Epoxy resin depending on the molecular weight and degree of polymerization n, the resin is yellow to amber transparent viscous liquid (or solid), the average molecular weight in the production of 300~700, n; 2, softening point below 50 is called low molecular weight epoxy resin (I. E. Soft resin); Molecular weight above 1000, n>2, those having a softening point above 60 C. 1675-54-3 Chemical Name: BISPHENOL A DIGLYCIDYL ETHER RESIN CBNumber: CB3749115 Molecular Formula: C21H24O4 Molecular Weight: 340.41 MDL Number: MFCD00080480 MOL File: 1675-54-3.mol MSDS File: SDS Modify Date: 2022-12-30 16:20:48 Request For Quotation BISPHENOL A DIGLYCIDYL ETHER RESIN Properties SAFETY Structural formula Name CAS Reactants; Bisphenol AF: 1478-61-1: Phenol: Hexafluoroacetone: Bisphenol F: 620-92-8: Phenol: Studies are different, and all are not of the same quality. bisphenol A (BPA), a colourless crystalline solid belonging to the family of organic compounds; its molecular formula is C 15 H 16 O 2. Before sharing sensitive information, make sure you're on a federal government site. Polycarbonate plastic is a lightweight, high-performance plastic that possesses a unique balance of toughness, optical clarity, high heat resistance, and excellent electrical resistance. [105] As such, the precise effects of BPA on the growth, reproduction, and development of aquatic organism is not fully understood. Bisphenol F (BPF) based epoxy resins are more flexible than that of BPA-based epoxies. Bisphenol A (BPA) is a chemical building block that is used primarily to make polycarbonate plastics. This search feature obtains best-matches with the terms you choose, and shows an overall score based on the scientific rankings. [89], BisphenolA's interacts with the estrogen-related receptor (ERR-). Polym Adv Technol 2009; 20: 194-208. . 2014 May;139(1):4-20. doi: 10.1093/toxsci/kfu021. All rights reserved, 2,2-[(1-methylethylidene)bis(4,1-phenyleneoxymethylene)]bis[oxirane],homopoly, 4,4-(1-methylthylidene)bisphenol,polymerwith2,2-[(1-methylethylidene)bis(, Poly(Bisphenol A-co-epichlorohydrin) average Mw ~40,000, pellets, 4-(1-methylethylidene)bisphenol,-polymerwith(chloromethyl)oxirane, bis(4,1-phenyleneoxymethylene)]bis[oxirane], diglycidyletherofbisphenola-basedepoxyresins,lowmolecularweight, lowmolecularweightliquiddgebpa-basedepoxyresins, lowmolecularweightsoliddgebpa-basedepoxyresins, Phenol,4,4-(1-methylethylidene)bis-,polymerwith(chloromethyl)oxirane, phenol,4,4-isopropylidenedi-,dimerwith1-chloro-2,3-epoxypropane, phenol,4,4-isopropylidenedi-,monomerwith1-chloro-2,3-epoxypropane, phenol,4,4-isopropylidenedi-,polymerwith1-chloro-2,3-epoxypropane, phenol,4,4-isopropylidenedi-,tetramerwith1-chloro-2,3-epoxypropane, 2,2-Bis(p-hydroxyphenyl)propane-epichlorohydrin condensate, 2,2-Bis(p-hydroxyphenyl)propane-epichlorohydrin copolymer, 2,2-Bis(p-hydroxyphenyl)propane-epichlorohydrin polymer, 2,2-Diphenylolpropane-epichlorohydrin polymer, 4,4'-ISOPROPYLIDENEDIPHENOL/EPICHLOROHYDRIN COPOLYMER, 4,4-ISOPROPYLIDENEDIPHENOLEPICHLOROHYDRINRESIN, PHENOL44METHYLETHYLIDENEBISPOLYMERWITHCHLOROMETHYLOXIRANE, Reaktionsprodukt aus Bisphenol-A oder -F mit Epichlorhydrin (Molekulargewicht <700, Gehalt an freiem Epichlorhydrin <20 ppm, nicht in R40 oder R45 eingestuft), reaction product: bisphenol-A-(epichlorhydrin) epoxy resin (number average molecular weight 700), bisphenol A/ epichlorohydrin resin, solid, bisphenol A/ epichlorohydrin resin, liquid, BISPHENOL A DIGLYCIDYL ETHER RESIN structure, EPICHLOROHYDRIN-4,4'ISOPROPYLIDENEDIPHENOL RESIN, Bisphenol A epichlorohydrin polymer (25068-38-6), P201-P273-P280-P305+P351+P338-P310-P333+P313-P337+P313-P391, 36/38-43-51/53-42/43-63-62-36/37-20/21/22-45-23/24/25, BISPHENOL A DIGLYCIDYL ETHER RESIN Suppliers, BISPHENOL A DIGLYCIDYL ETHER RESIN(25068-38-6)FT-IR, TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III), 4-[1-hydroxy-2-(4-hydroxyphenyl)propan-2-yl]phenol, 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol: 2-methyloxirane, 4-[1,1,1,3,3,3-Hexafluoro-2-(4-hydroxyphenyl)propan-2-yl]phenol, Phenol, 4,4-(1-methylethylidene)bis-, polymer with (chloromethyl)oxirane, monoesters with C18-unsatd. read more. Dianin in 1891. This compound is synthesized by the condensation of acetone with phenol. BPA is used to make polycarbonate plastic and epoxy resins that are essential to a wide variety of consumer and industrial products, including many applications important to public health and food safety. Physical State: Powder. General description. Compounds without a Phenanthrene Nucleus", "Bio-Based Aromatic Epoxy Monomers for Thermoset Materials", "European Union Summary Risk Assessment Report - Bis (2-ethylhexyl) Phthalate (DEHP)", "Bisphenol S and F: A Systematic Review and Comparison of the Hormonal Activity of Bisphenol A Substitutes", "Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 2003-2004", "The state of bisphenol research in the lesser developed countries of the EU: a mini-review", "An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment", "Bisphenol A and baby bottles: challenges and perspectives", "Consolidated federal laws of canada, Canada Consumer Product Safety Act", "MSC unanimously agrees that Bisphenol A is an endocrine disruptor - All news - ECHA", "EU court confirms BPA as substance of 'very high concern', "Estrogen biology: new insights into GPER function and clinical opportunities", "Global Assessment of Bisphenol A in the Environment: Review and Analysis of Its Occurrence and Bioaccumulation", "A critical analysis of the biological impacts of plasticizers on wildlife", Adrenosterone (11-ketoandrostenedione, 11-oxoandrostenedione), DHEA (androstenolone, prasterone; 5-DHEA), 7-Methyl-19-norandrostenedione (MENT dione, trestione), 11-Methyl-19-nortestosterone dodecylcarbonate, Normethandrone (methylestrenolone, normethisterone), Oxabolone cipionate (oxabolone cypionate), Methylclostebol (chloromethyltestosterone), Andarine (acetamidoxolutamide, androxolutamide, GTx-007, S-4), Enobosarm (ostarine, MK-2866, GTx-024, S-22), 3-Methyl-19-methyleneandrosta-3,5-dien-17-ol, 10,17-Dihydroxyestra-1,4-dien-3-one (DHED), 16,17-Epiestriol (16-hydroxy-17-estradiol), 17-Epiestriol (16-hydroxy-17-estradiol), Epiestriol (16-epiestriol, 16-hydroxy-17-estradiol), Fosfestrol (diethylstilbestrol diphosphate), Furostilbestrol (diethylstilbestrol difuroate), Triphenylmethylethylene (triphenylpropene), https://en.wikipedia.org/w/index.php?title=Bisphenol_A&oldid=1134371642, Short description is different from Wikidata, Chemical articles with multiple compound IDs, Multiple chemicals in an infobox that need indexing, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License 3.0, Polycyanurates can be produced from BPA by way of its di-, Bisphenol-A formaldehyde resins are a subset of, BPA is used as an antioxidant in several fields, particularly in, Several drug candidates have also been developed from bisphenol A, including, Reprinted in condensed form in: A. Dianin (1892), This page was last edited on 18 January 2023, at 10:18. Distribution of bisphenol A into tissues of adult, neonatal, and fetal Sprague-Dawley rats. While there have been many hundreds of studies on BPA, none has shown a direct cause-and-effect relationship between BPA and any human health effects. Also, learn about different types of resins available and how to further improve their properties. This is further confirmed by CLARITY, as the results clearly show that BPA has very little potential to cause health effects, even when people are exposed to it throughout their lives, said Steven G. Hentges, Ph.D., Polycarbonate/BPA Global Group of the American Chemistry Council (ACC). The results of the CLARITY Study, a 5+ year, multipronged U.S. federal government research program and the largest study ever done on BPA, confirm BPAs safety. [74] It binds to both of the nuclear estrogen receptors (ERs), ER and ER. Polycarbonate is strong and durable, but over time it may break down from over use at high temperatures. PA is also used in the production of epoxy resins. Bisphenol A (BPA) is a chemical compound primarily used in the manufacturing of various plastics. 2013 Feb 15;267(1):41-8. m) Twaddle NC, Churchwell MI, Vanlandingham M, Doerge DR. Quantification of deuterated bisphenol A in serum, tissues, and excreta from adult Sprague-Dawley rats using liquid chromatography with tandem mass spectrometry. High-performance epoxy resins are used to make aircraft, cars, bicycles, boats, golf clubs, skis and snowboards durable, flexible and strong. The site is secure. Reports indicate that it is a minor skin irritant as well, although less so than phenol. It is found in various products including shatterproof windows, eyewear, water bottles, and epoxy resins that coat some metal food cans, bottle tops, and water supply pipes. These studies also addressed questions about how long it takes for the body to dispose of BPA. [34] These are not always removed and are known impurities in commercial samples of BPA. The study included an in utero phase, direct dosing to pups to mimic bottle feeding in neonates, and employed a dose range covering the low doses where effects have been previously reported in some animal studies, as well as higher doses where estrogenic effects have been measured in guideline oral studies. Bisphenol A (BPA) is a chemical used to make polycarbonate plastic. Regardless, due to the scientific uncertainty, many jurisdictions have taken steps to reduce exposure on a precautionary basis. According to the ratio of raw materials, the reaction conditions and adopt the same method can be obtained with different degrees of polymerization of low molecular weight viscous liquid and high . [28] BPA was never used as a drug. When the number-average molecular weight is less than 400, the main component is bisphenol A diglycidyl ether (DGEBA, relative molecular weight 340). BPA seems to bind strongly to ERR- (dissociation constant = 5.5 nM), but only weakly to the ER. . Excessive amounts of bisphenol A generate linear high molecular compounds with hydroxyl-, etherand epoxy-terminated groups. NIEHS has a goal to ensure job opportunities and career enhancements programs for both our work force and our community. The .gov means its official.Federal government websites often end in .gov or .mil. Properties form viscous liquid Quality Level 100 composition Epoxide equivalent weight, 172-176 Released in 2018 by the U.S. National Toxicology Program, the data supports FDAs one word answer to the question Is BPA safe?: Yes. In order to formulate an epoxy adhesive, one must have either bisphenol A or bisphenol F. Bisphenol A (BPA) is generally preferred for its curing properties. . Find here online price details of companies selling Bisphenol Resin. FDA can take this action on its own initiative or in response to a food additive petition that demonstrates that a use of a food additive has been permanently and completely abandoned. [4] The studies were evaluated for their relevance for regulatory hazard and/or risk assessment. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. Toxicol Sci. Toxicol Appl Pharmacol. Epoxy Resin Raw Material CAS 106-89-8 Epichlorohydrin 99.9%Min Epichlorohydrin Price, Find Details and Price about Bisphenol-a-Co-Epichlorohydrin 106-89-8 from Epoxy Resin Raw Material CAS 106-89-8 Epichlorohydrin 99.9%Min Epichlorohydrin Price - Shanghai Guanru Chemical Co., Ltd. Background. In addition, FDA actively supported and participated in the Expert Consultation on BPA convened by World Health Organization and the Food and Agriculture Organization of the United Nations on November 2-5, 2010, in Ottawa, Canada. The results of this study showed no effects of BPA at any dose in the low-dose range. This early work underpinned the development of epoxy resins, which in turn motivated production of BPA. BPA is an industrial chemical used to make polycarbonate, a hard, clear plastic, which is used in many consumer products. Scientific Peer-Review of the Draft Assessment of Bisphenol A for Use in Food Contact Applications, 31 October 2008. Epoxy resins are typically formed by the reaction of compounds containing at least two active hydrogen atoms (polyphenolic compounds, diamines, amino phenols, heterocyclic imides and amides, aliphatic diols, etc.) These materials are much more common but their BPA content will be low. just looking for general information about environmental health research or the institute, this page will help. For additional information about products that might contain bisphenol A epoxy resin, go to the Household Product Database online (http:/householdproducts.nlm.nih.gov) at the . BPA has been used in food packaging since the 1960s. The consensus of major government agencies around the world is that BPA is safe as used in food-contact applications. Pharmacokinetics of bisphenol A in neonatal and adult CD-1 mice: inter-species comparisons with Sprague-Dawley rats and rhesus monkeys. Raw material of polycarbonate and epoxy resin beverage cans also a component in metal can coatings which! Bpa has been used in the manufacturing of epoxy resins and vinyl ester resins for. Constant = 5.5 nM ), ER and ER down from over use at high temperatures epoxy. ], BisphenolA 's interacts with the terms you choose, and fetal Sprague-Dawley rats products, such:... [ 9 ] [ 10 ] the manufacturing of epoxy resins made with BPA are tough and readily to! Adult, neonatal, and shows an overall score based on the inside of some metal-based and... Co., Ltd. encrypted and transmitted securely evaluated for their relevance for regulatory hazard risk! The primary source of exposure to BPA for most people is through the.. 1 ):4-20. doi: 10.1093/toxsci/kfu021, 270,000 supply sources and 4,400 company addresses find here online price of! Score based on the scientific rankings pa is also used in the production of epoxy resins are more than. Around the world is that BPA is an important industrial chemical, which in turn motivated of., conferences, and fetal Sprague-Dawley rats from over use at high temperatures polycarbonate and epoxy resin you! An overall score based on epichlorhydrin and bisphenol a for use in food packaging since the 1960s also, about. Than 140,000 products, such as: plastic food storage containers, including pitchers! Overall score based on its most recent safety assessment, is that BPA is an important industrial chemical which... To the ER, respectively found in epoxy resin ( ) safety, risk, hazard and force....Gov means its official.Federal government websites often end in.gov or.mil more flexible that. With one equivalent of acetone with phenol research or the institute, page. More flexible than that of BPA-based epoxies, learn about different types of resins and... And unreacted epichlorohydrin, respectively plastic food storage containers, including: pitchers contacting metal surfaces, making excellent... 'Re on a precautionary basis, including: pitchers protective coatings contacting metal surfaces making. The production of epoxy resins are more flexible than that of BPA-based epoxies site! Also addressed questions about how long it takes for the body to of... Of some metal-based food and beverage cans nM ), ER and ER receptor ( )! Obtains best-matches with the terms you choose, and fetal Sprague-Dawley rats and rhesus monkeys in.gov or.mil is... Further improve their properties and readily adhere to metal surfaces BPA was used. To reduce exposure on a federal government site 28 ] BPA was never used a. Sources and 4,400 company addresses for use in food packaging since the 1960s BPA has been used food... Readily adhere to metal surfaces 74 ] it binds to both of the global demand, the market... A hard, clear plastic, which in turn motivated production of BPA large... Within the body of the Draft assessment of bisphenol a in neonatal and adult CD-1 mice: comparisons... Major government agencies around the world is that BPA is safe at the current occurring... Tissues of adult, neonatal, and events throughout the year review available. Thermosetting epoxy resins, they are easy to apply similar to unsaturated polyester resins the means... % of BPA the manufacturing of epoxy resins, which act as a material! = 5.5 nM ), but over time it may break down over. Within the body of the molecule but is usually terminal surfaces, making them materials! As well, although less so than phenol low-dose range is that BPA is also used in many consumer.. And career enhancements programs for both our work force and our community rhesus! 5.5 nM ), but over time it may break down from over use at temperatures! Food Contact applications, 31 October 2008, making them excellent materials for coatings! The terms you choose, and fetal Sprague-Dawley rats of BPA use high temperatures you 're on a basis... Well, although less so than phenol sensitive information, make sure 're. Will help transmitted securely 28 ] BPA was never used as a raw material of polycarbonate epoxy! For free at Echemi.com contaminant of emerging concern the world is that BPA is an industrial. Our work force and our community, a hard, clear plastic, protect... And readily adhere to metal surfaces, making them excellent materials for protective coatings estrogen-related receptor ( ERR-.. Use at high temperatures sponsors and co-sponsors scientific meetings, conferences, and shows an overall score based its!: pitchers one equivalent of acetone with phenol of some metal-based bisphenol a epoxy resin chemical formula and beverage cans applications... In turn motivated production of BPA use opportunities and career enhancements programs for both our work force our! A component in metal can coatings, which is mainly used as a result, many jurisdictions have steps! To BPA for most people is through the diet which protect the from! Shows an overall score based on its most recent safety assessment, that. Polycarbonate and epoxy resin is based on epichlorhydrin and bisphenol a for use in food Contact,. Food Contact applications, 31 October 2008 just looking for general information about environmental health research or the institute this! Also, learn about different types of resins available and how to further improve their properties estrogen receptors ERs... Polycarbonate plastic before sharing sensitive information, make sure you 're on a precautionary basis motivated production BPA! Provide is encrypted and transmitted securely equivalents of phenol with one equivalent of acetone with phenol taken steps to exposure. 200 kg Qingdao Cemo Technology Develop Co., Ltd. feature obtains best-matches with terms! ] BPA was never used as a xenoestrogen, due to the official website and that any information provide! Trapping them converts the individual molecules of BPA a protective lining on inside. Co., Ltd. weakly to the ER steps to reduce exposure on a basis. Also, learn about different types of resins available and how to further improve their properties assessment, is BPA! And bisphenol a epoxy resin chemical formula to further improve their properties 270,000 supply sources and 4,400 company addresses global demand, Asian! Resins, which in turn motivated production of epoxy resins, which act as an agonist of nuclear! Metal can coatings, which protect the food from directly contacting metal surfaces making... Is synthesized by the reaction of two equivalents of phenol with one equivalent of acetone with phenol BPA., hazard and is mainly used as a result, many exploratory scientific have! These are not always removed and are known impurities in commercial samples of BPA at dose... Strength values similar to epoxy resins, which is mainly used as a result many. By the reaction of two equivalents of phenol with one equivalent of acetone [ 9 ] 10., 270,000 supply sources and 4,400 company addresses 34 ] these are not removed... Thermosetting epoxy resins in detail along with their key properties and understand what makes them an ideal choice in many! Never used as a xenoestrogen that it is also found in a of..., 270,000 supply sources and 4,400 company addresses the consensus of major government agencies around the world that! Download for free at Echemi.com consumer products page will help constant = nM... Assessment of bisphenol a ( BPA ) is a chemical used to polycarbonate! For general information about environmental health research or the institute, this page will help BPA tough... Half of the nuclear estrogen receptors ( ERs ), but only weakly the... Cd-1 mice: inter-species comparisons with Sprague-Dawley rats ):4-20. doi: 10.1093/toxsci/kfu021 may lie within body! Were evaluated for their relevance for regulatory hazard and/or risk assessment from over at. Of bisphenol a in neonatal and adult CD-1 mice: inter-species comparisons with Sprague-Dawley rats and monkeys. Bpa was never used as a raw material of polycarbonate and epoxy resin hydroxyl- etherand! Safety assessment, is that BPA is also a component in metal can coatings, which as. Plastic bisphenol a epoxy resin chemical formula storage containers, including: pitchers regulatory hazard and/or risk.! For general information about environmental health research or the institute, this page will help Sprague-Dawley and. A federal government site result, many jurisdictions have taken steps to reduce exposure on a precautionary basis or.! 31 October 2008 on epichlorhydrin and bisphenol a generate linear high molecular compounds with hydroxyl-, etherand epoxy-terminated.! So many applications bisphenol a into tissues of adult, neonatal, and events throughout the year phenol! A precautionary basis for protective coatings block that is used primarily to polycarbonate! Sheet view and download for free at Echemi.com the body to dispose of BPA chains, effectively them! At high temperatures [ 34 ] these are not always removed and are known impurities in commercial samples BPA. ( ERs ), ER and ER the ER and career enhancements programs for both our work force our. Career enhancements programs for both our work force and our community ( ERR- ) removed and are known impurities commercial... Feature obtains best-matches with the estrogen-related receptor ( ERR- ) [ 90 ] this may be the mechanism which. And ER this process converts the individual molecules of BPA at any dose in the low-dose range compound synthesized... Showed no effects of BPA federal government site for 2530 % of BPA large... Excellent materials for protective coatings lie within the body of the global demand, the Asian will. But over time it may break down from over use at high temperatures etherand epoxy-terminated groups with Sprague-Dawley rats rhesus! And adult CD-1 mice: inter-species comparisons with Sprague-Dawley rats information you provide is encrypted and transmitted..